Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast
نویسندگان
چکیده
منابع مشابه
Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast.
RNA interference (RNAi) is widespread in eukaryotes and regulates gene expression transcriptionally or post-transcriptionally. In fission yeast, RNAi is tightly coupled to template transcription and chromatin modifications that establish heterochromatin in cis. Exogenous double-stranded RNA (dsRNA) triggers seem to induce heterochromatin formation in trans only when certain silencing proteins a...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2010
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2009.273